XL541 [CAS 1221878-06-3]

XL541 is a potent, selective S1P1 antagonist. XL541 inhibits GDP-GTP exchange. XL541 causes frank surface hemorrhaging of tumors. XL541 collaborates with Paclitaxel to exhibit antitumor activity against breast cancer and lung cancer[1].

[1221878-06-3]

C28H25F2N5O3

517.53

FC1=CC=C(OC2=CC=C(NC([C@H]3N(C(CN4C=CN=N4)=O)C[C@H](CC5=CC=C(F)C=C5)C3)=O)C=C2)C=C1

LPL Receptor

Room temperature