Y-29794 (oxalate) [CAS 146794-84-5]

Y-29794 oxalate is a selective, orally active and blood-brain barrier permeable non-peptide prolyl endopeptidase inhibitor. Y-29794 oxalate blocks the IRS1-AKT-mTORC1 pathway and inhibits tumor growth. Y-29794 oxalate is also effective in inhibiting the progression of Aβ-like deposition in the hippocampus of aging-accelerated mice (SAM) [1][2][3].

[146794-84-5]

C25H36N2O5S2

508.69

O=C(C1=CC=CS1)C2=C(N=C(C(C)C)C=C2)SCCCCCCCCN(C)C.OC(C(O)=O)=O

Prolyl Endopeptidase (PREP)

10 mM in DMSO

Room temperature