YD1342

YD1342 is a prodrug of YD1130, which exhibits potent inhibitory effects on cellular substrate methylation, breast cancer cell clonogenicity, and tumor growth in animal models, exceeding or matching known PRMT4-specific inhibitors.[1].

C33H39BrN6O6S

727.67

NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](CSCCN(C(CC(C)(C)C(C(C(C)=C4C)=O)=C(C)C4=O)=O)CC5=CC(Br)=CC=C5)[C@@H](O)[C@H]3O

Histone Methyltransferase

Room temperature