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SKU:QM-0114937-01
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YDR1 is a potent PROTAC SMARCA2 degrader, with the DC50 of 7.7 nM. YDR1 plays an important role in SMARCA4 mutant cancers (Sturcture Note: (Blue: Cereblon ligand , Black: linker; Pink: SMARCA2 ligand (HY-44012B) ).
[2951015-31-7]
C44H49FN10O5
816.92
O=C(N(C1CCC(NC1=O)=O)C2=O)C3=C2C=CC(N4CCN(CC5CCN(C6=C(F)C=C(CN7CCN(C8=C(N)N=NC(C9=C(O)C=CC=C9)=C8)CC7)C=C6)CC5)CC4)=C3
Epigenetic Reader Domain; PROTACs
98.03
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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YDR1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.