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YM-359445 (dihydroxybutanedioate) [CAS 1020067-28-0]
YM-359445 (dihydroxybutanedioate) [CAS 1020067-28-0]
SKU:QM-0004262
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Product Details
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Description
YM-359445 dihydroxybutanedioate is an orally active VEGFR2 tyrosine kinase inhibitor, with an IC50 of 8.5 nM. YM-359445 dihydroxybutanedioate shows a complete inhibition of vascular permeability induced by VEGF. YM-359445 dihydroxybutanedioate shows antitumor activity against both lung cancer and Paclitaxel -resistant colon cancer[1].
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CAS Number
[1020067-28-0]
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Molecular Formula
C32H34N6O8S
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Molecular Weight
662.71
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Smiles
OC([C@H](O)[C@@H](O)C(O)=O)=O.O=C1/C(C2=CC=C(/C=N/OCC3=CSC=N3)C=C2N1)=C4NC5=CC=C(CN6CCN(C)CC6)C=C5C=C\4
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Target
VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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YM-359445 (dihydroxybutanedioate) [CAS 1020067-28-0]
YM-359445 (dihydroxybutanedioate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.