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YM928 [CAS 190842-36-5]
YM928 [CAS 190842-36-5]
SKU:QM-0087703
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Product Details
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Description
YM928 is an orally active and noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist. YM928 inhibits AMPA receptor-mediated toxicity in primary rat hippocampal cultures with an IC50 value of 2 μM. YM928 blocks AMPA-induced intracellular calcium influx with an IC50 value of 3 μM and antagonizes AMPA-induced inward currents with an IC50 value of 1 μM. YM928 is promising for research of neurological disorders[1].
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CAS Number
[190842-36-5]
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Molecular Formula
C14H10ClN3OS
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Molecular Weight
303.77
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Smiles
O=C1N=C(SC2=NC=CC=C12)N(C)C3=CC=C(C=C3)Cl
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Target
IGluR
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Shipping Conditions
Room temperature
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YM928 [CAS 190842-36-5]
YM928 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.