YTHDC1-IN-1 [CAS 2995344-53-9]

YTHDC1-IN-1 is a selective YTHDC1 inhibitor with a Kd of 49 nM and an IC50 of 0.35 μM. YTHDC1-IN-1 can inhibit the proliferation and induce apoptosis of acute myeloid leukemia cell lines. YTHDC1-IN-1 has anti-tumor activity[1].

[2995344-53-9]

C13H11Cl2N5

308.17

CNC1=NC(Cl)=NC2=C(CC3=CC=CC(Cl)=C3)NN=C21

Apoptosis; DNA/RNA Synthesis; PARP

99.44

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years (Powder)

Blue Ice