Z-FA-FMK [CAS 197855-65-5]

Z-FA-FMK ((1S) -Z-FA-FMK) is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs) . Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host[1][2][3].

[197855-65-5]

C21H23FN2O4

386.42

O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(NC(C)C(CF)=O)=O

Apoptosis; Caspase; Cathepsin; SARS-CoV

Caspase 2; Caspase 3; Caspase 6; Caspase 7; Cathepsin B; Cathepsin L

99.14

DMSO : 250 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335