Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse[1].
CAS Number
[852222-94-7]
Molecular Formula
C18H17N3O4S
Molecular Weight
371.41
Smiles
O=C1N=C(NC2=C1C=CC=C2)SCC(NC3=CC=C(C=C3OC)OC)=O
Target
Mitochondrial Metabolism; p38 MAPK
Purity
98.13
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)