Z218484536 [CAS 1223877-07-3]

Name: Z218484536 [CAS 1223877-07-3]
Brand: QuantiMol
SKU: QM-0008004-01
Price: 325.81 GBP
Availability: InStock

Size 5 mg 10 mM - 1 mL 10 mg 25 mg 50 mg

SKU:QM-0008004-01

£325.81 GBP

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Product Details

Description
Z218484536 is a selective and brain-penetrant phosphoserine phosphatase (PSPH) inhibitor. Z218484536 binds to PSPH with a Kd value of approximately 0.23 μM. Z218484536 reduces L-serine and D-serine levels in astrocytes. Z218484536 is able to suppress spontaneous epileptic seizures without causing serious side effects. Z218484536 also shows good anti-epileptic effects in the temporal lobe epilepsy (TLE) model[1].
CAS Number
[1223877-07-3]
Molecular Formula
C11H10FN5O
Molecular Weight
247.23
Smiles
O=C(N/N=C/C1=CNN=C1C2=CC=C(F)C=C2)N
Target
Phosphatase
Concentration
10mM
Purity
97.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0008004-01	5 mgQM-0008004-01 £325.81/ea	£0.00	Quantity	£325.81/ea	£0.00

10 mM - 1 mLQM-0008004-02	10 mM - 1 mLQM-0008004-02 £353.75/ea	£0.00	Quantity	£353.75/ea	£0.00

10 mgQM-0008004-03	10 mgQM-0008004-03 £501.98/ea	£0.00	Quantity	£501.98/ea	£0.00

25 mgQM-0008004-04	25 mgQM-0008004-04 £890.78/ea	£0.00	Quantity	£890.78/ea	£0.00

50 mgQM-0008004-05	50 mgQM-0008004-05 £1,392.58/ea	£0.00	Quantity	£1,392.58/ea	£0.00

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Z218484536 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.