Name: Zelasudil [CAS 2365193-22-0]
Brand: QuantiMol
SKU: QM-0149875-01
Price: 294.22 GBP
Availability: InStock

Product Details

Description
Zelasudil (RXC007) is an orally active, highly selective small molecule Rho-associated coiled-coil containing protein kinase 2 (ROCK2) inhibitor with anti-fibrotic efficacy. Zelasudil elicits positive immunomodulatory effects in metastatic pancreatic tumors with increase of CD8+ and CD4+ T cell infiltrate into the tumor cortex and reduction in immunosuppressive FOXP3+ regulatory T cells at the tumor border. Zelasudil is promising for research of pancreatic ductal adenocarcinoma[1][2][3][4].
CAS Number
[2365193-22-0]
Molecular Formula
C22H21F2N7O
Molecular Weight
437.45
Smiles
O=C(C1=CC=C(C2=NN(C)C(NC3=CC=C4NN=CC4=C3C5CC5)=N2)C=C1)NCC(F)F
Target
ROCK
Purity
99.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0149875-01	5 mgQM-0149875-01 £294.22/ea	£0.00	Quantity	£294.22/ea	£0.00

10 mgQM-0149875-02	10 mgQM-0149875-02 £431.51/ea	£0.00	Quantity	£431.51/ea	£0.00

50 mgQM-0149875-03	50 mgQM-0149875-03 £916.29/ea	£0.00	Quantity	£916.29/ea	£0.00

100 mgQM-0149875-04	100 mgQM-0149875-04 £1,267.43/ea	£0.00	Quantity	£1,267.43/ea	£0.00

250 mgQM-0149875-05	250 mgQM-0149875-05 £1,882.22/ea	£0.00	Quantity	£1,882.22/ea	£0.00

500 mgQM-0149875-06	500 mgQM-0149875-06 £2,685.34/ea	£0.00	Quantity	£2,685.34/ea	£0.00

1 gQM-0149875-07	1 gQM-0149875-07 £3,753.32/ea	£0.00	Quantity	£3,753.32/ea	£0.00

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Zelasudil [CAS 2365193-22-0]

Zelasudil is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.