ZK159222 [CAS 156965-15-0]

ZK159222, a 25-carboxylic ester analogue of 1α,25- (OH) 2D3, is a potent 1α,25- (OH) 2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character[1].

[156965-15-0]

C32H48O5

512.72

O=C(C1([C@H](O)/C=C/[C@H]([C@H]2CC[C@@]3([H])/C(CCC[C@]23C)=C/C=C4C([C@@H](O)C[C@H](O)C\4)=C)C)CC1)OCCCC

VD/VDR

99.23

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature