ZLJ-6 [CAS 1051931-39-5]

ZLJ-6 is a dual COX and 5-LOX inhibitor with oral activity. The IC50 values for COX-1, COX-2 and 5-LOX were 0.73, 0.31 and 0.99 μM, respectively. ZLJ-6 has anti-inflammatory and analgesic activity[1][1].

[1051931-39-5]

C13H17N3O6S2

375.42

CS(=O)(O)=O.CN(C(N)=NC/1=O)C1=C/C2=CC=C(C=C2)S(C)(=O)=O

COX; Lipoxygenase

5-LOX; COX-1; COX-2

10 mM in DMSO

Room temperature