ZLM-66 [CAS 3033486-43-7]

ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTIs) with an IC50 of 41 nM for wild-type (WT) HIV-1 reverse transcriptase and an EC50 value of 13 nM for wild-type HIV-1. ZLM-66 is a Doravirine analogs. ZLM-66 can be used for the research of AIDS[1].

[3033486-43-7]

C24H18F3N5O3

481.43

CN1C(CN(C=CC(C(F)(F)F)=C2OC3=CC(C#N)=CC(C4=CC(C)=CC=C4)=C3)C2=O)=NNC1=O

HIV

HIV-1

10 mM in DMSO

Room temperature