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ZZM-1220

ZZM-1220

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SKU:QM-0151936-01

£493.48 GBP
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  • Description

    ZZM-1220 is a histone lysine methyltransferase G9a/GLP covalent inhibitor with IC50s of of 458 nM and 924 nM, respectively. ZZM-1220 inhibits H3K9me2 in cells and significantly induces apoptosis of triple-negative breast cancer (TNBC) cells and blocks the cell cycle in the G2/M phase[1].

  • Molecular Formula

    C25H29N5O3

  • Molecular Weight

    447.53

  • Smiles

    C=CC(NC1=CC(C2=NC3=CC(OC)=C(C=C3C(NC4CCN(CC4)C)=N2)OC)=CC=C1)=O

  • Target

    Apoptosis; Histone Methyltransferase

  • Isoform

    EHMT1/GLP/KMT1D; EHMT2/G9a/KMT1C

  • Purity

    98.74

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

Your cart
Variant Variant total Quantity Price Variant total
1 mgQM-0151936-01
1 mgQM-0151936-01
£493.48/ea
£0.00
£493.48/ea £0.00
5 mgQM-0151936-02
5 mgQM-0151936-02
£1,292.94/ea
£0.00
£1,292.94/ea £0.00
10 mgQM-0151936-03
10 mgQM-0151936-03
£1,665.95/ea
£0.00
£1,665.95/ea £0.00
25 mgQM-0151936-04
25 mgQM-0151936-04
£2,472.71/ea
£0.00
£2,472.71/ea £0.00
50 mgQM-0151936-05
50 mgQM-0151936-05
£3,199.28/ea
£0.00
£3,199.28/ea £0.00
100 mgQM-0151936-06
100 mgQM-0151936-06
£3,987.82/ea
£0.00
£3,987.82/ea £0.00

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ZZM-1220

ZZM-1220 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.