1,2,4-Trihydroxybenzene (Standard) [CAS 533-73-3]
1,2,4-Trihydroxybenzene (Standard) [CAS 533-73-3]
SKU:QM-0084429-01
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Product Details
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Description
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) (Standard) is the analytical standard of 1,2,4-Trihydroxybenzene. This product is intended for research and analytical applications. 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2α phosphorylation, activates the PERK-eIF2α signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm[1][2][3][4].
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CAS Number
[533-73-3]
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Molecular Formula
C6H6O3
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Molecular Weight
126.11
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Smiles
OC1=CC=C(O)C=C1O
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Target
Apoptosis; Eukaryotic Initiation Factor (eIF) ; PERK; Potassium Channel; Reference Standards
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Isoform
EIF2
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H318-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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1,2,4-Trihydroxybenzene (Standard) [CAS 533-73-3]
1,2,4-Trihydroxybenzene (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.