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1- (4-Hydroxy-2-methoxyphenyl) -3- (4-hydroxy-3-prenylphenyl) [CAS 376362-03-7]
1- (4-Hydroxy-2-methoxyphenyl) -3- (4-hydroxy-3-prenylphenyl) [CAS 376362-03-7]
SKU:QM-0085782
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Product Details
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Description
1- (4-Hydroxy-2-methoxyphenyl) -3- (4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes[1].
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CAS Number
[376362-03-7]
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Molecular Formula
C21H26O3
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Molecular Weight
326.43
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Smiles
OC1=CC=C(CCCC2=CC=C(O)C=C2OC)C=C1C/C=C(C)\C
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Target
Phosphatase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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1- (4-Hydroxy-2-methoxyphenyl) -3- (4-hydroxy-3-prenylphenyl) [CAS 376362-03-7]
1- (4-Hydroxy-2-methoxyphenyl) -3- (4-hydroxy-3-prenylphenyl) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.