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1-Aminocyclopropane-1-carboxylic acid [CAS 22059-21-8]

1-Aminocyclopropane-1-carboxylic acid [CAS 22059-21-8]

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QM-0155822-01

£89.13 GBP
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Product Details

  • Description

    1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.[1][2][3].

  • CAS Number

    [22059-21-8]

  • Molecular Formula

    C4H7NO2

  • Molecular Weight

    101.1

  • Smiles

    O=C(O)C1(N)CC1

  • Target

    Endogenous Metabolite

  • Purity

    99.76

  • Solubility

    DMSO : < 1 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    Store at room temperature 3 years

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
500 mgQM-0155822-01
500 mgQM-0155822-01
£89.13/ea		 £0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0155822-02
10 mM - 1 mLQM-0155822-02
£94.75/ea		 £0.00
£94.75/ea £0.00
1 gQM-0155822-03
1 gQM-0155822-03
£121.75/ea		 £0.00
£121.75/ea £0.00
5 gQM-0155822-04
5 gQM-0155822-04
£238.32/ea		 £0.00
£238.32/ea £0.00
10 gQM-0155822-05
10 gQM-0155822-05
£294.22/ea		 £0.00
£294.22/ea £0.00
25 gQM-0155822-06
25 gQM-0155822-06
£441.23/ea		 £0.00
£441.23/ea £0.00
50 gQM-0155822-07
50 gQM-0155822-07
£520.20/ea		 £0.00
£520.20/ea £0.00
100 gQM-0155822-08
100 gQM-0155822-08
£614.98/ea		 £0.00
£614.98/ea £0.00
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1-Aminocyclopropane-1-carboxylic acid [CAS 22059-21-8]

1-Aminocyclopropane-1-carboxylic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.