1-Aminocyclopropane-1-carboxylic acid (Standard) [CAS 22059-21-8]
1-Aminocyclopropane-1-carboxylic acid (Standard) [CAS 22059-21-8]
SKU:QM-0155823-01
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Product Details
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Description
1-Aminocyclopropane-1-carboxylic acid (Standard) is the analytical standard of 1-Aminocyclopropane-1-carboxylic acid. This product is intended for research and analytical applications. 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. In the presence of low concentrations (1 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a small molecule agonist of NMDA receptors with an EC50 of 0.7-0.9 μM. At high concentrations (10 μM) of glutamate, 1-Aminocyclopropane-1-carboxylic acid acts as a competitive antagonist of NMDA receptors with an EC50 of 81.6 nM. 1-Aminocyclopropane-1-carboxylic acid exerts neuroprotective activity by moderately activating NMDA receptors to prevent neuronal cell death in ischemic animal models. Additionally, 1-Aminocyclopropane-1-carboxylic acid is an antagonist of NMDA receptors, inducing blood pressure reduction and antioxidant effects in stroke-prone hypertensive rats. 1-Aminocyclopropane-1-carboxylic acid enhances object recognition memory and cognitive flexibility dependent on the prefrontal cortex, but does not affect impulsivity nor exhibit an antipsychotic-like profile. 1-Aminocyclopropane-1-carboxylic acid shows promise for research in the field of neurotoxicity.[1][2][3].
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CAS Number
[22059-21-8]
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Molecular Formula
C4H7NO2
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Molecular Weight
101.1
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Smiles
O=C(O)C1(N)CC1
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Target
Endogenous Metabolite; Reference Standards
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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1-Aminocyclopropane-1-carboxylic acid (Standard) [CAS 22059-21-8]
1-Aminocyclopropane-1-carboxylic acid (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.