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10-Hydroxy-2-decenoic acid [CAS 765-01-5]

10-Hydroxy-2-decenoic acid [CAS 765-01-5]

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SKU:QM-0200049-01

£51.91 GBP
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  • Description

    10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-α signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence[1][2][3][4][5][6][7][8][9][10].

  • CAS Number

    [765-01-5]

  • Molecular Formula

    C10H18O3

  • Molecular Weight

    186.25

  • Smiles

    O=C(O)/C=C/CCCCCCCO

  • Target

    AMPK; Apoptosis; Bacterial; Caspase; ERK; Fungal; GSK-3; Interleukin Related; MDM-2/p53; mTOR; NF-κB; TNF Receptor

  • Purity

    99.99

  • Solubility

    DMSO : ≥ 250 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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25 mgQM-0200049-01
25 mgQM-0200049-01
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10 mM - 1 mLQM-0200049-02
10 mM - 1 mLQM-0200049-02
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50 mgQM-0200049-03
50 mgQM-0200049-03
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10-Hydroxy-2-decenoic acid [CAS 765-01-5]

10-Hydroxy-2-decenoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.