10-Hydroxydecanoic acid [CAS 1679-53-4]
10-Hydroxydecanoic acid [CAS 1679-53-4]
SKU:QM-0200786-01
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Product Details
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Description
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5].
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CAS Number
[1679-53-4]
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Molecular Formula
C10H20O3
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Molecular Weight
188.26
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Smiles
O=C(O)CCCCCCCCCO
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Target
Autophagy; Caspase; Interleukin Related; MDM-2/p53; NF-κB; NO Synthase; Parasite; RANKL/RANK ; TNF Receptor
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Purity
99.77
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Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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10-Hydroxydecanoic acid [CAS 1679-53-4]
10-Hydroxydecanoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.