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12,14-Dichlorodehydroabietic acid [CAS 65281-77-8]
12,14-Dichlorodehydroabietic acid [CAS 65281-77-8]
SKU:QM-0062321-01
£514.13 GBP
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Product Details
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Description
12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, is a potent Ca2+-activated K+ (BK) channel opener. 12,14-Dichlorodehydroabietic acid blocks GABA-dependent chloride entry in mammalian brain and operates as a non-competitive GABAA antagonist. 12,14-Dichlorodehydroabietic acid increases cytosolic free Ca2+ and stimulates transmitter release[1][2].
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CAS Number
[65281-77-8]
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Molecular Formula
C20H26Cl2O2
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Molecular Weight
369.33
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Smiles
O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C(Cl)=C(C(C)C)C(Cl)=C3)O
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Target
GABA Receptor; Potassium Channel
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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12,14-Dichlorodehydroabietic acid [CAS 65281-77-8]
12,14-Dichlorodehydroabietic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.