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12-Ketochenodeoxycholic acid (Standard) [CAS 2458-08-4]

12-Ketochenodeoxycholic acid (Standard) [CAS 2458-08-4]

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SKU:QM-0051824

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  • Description

    Afatinib (Standard) is the analytical standard of Afatinib. This product is intended for research and analytical applications. Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4].

  • CAS Number

    [2458-08-4]

  • Molecular Formula

    C24H38O5

  • Molecular Weight

    406.56

  • Smiles

    C[C@H](CCC(O)=O)[C@H]([C@]12C)CC[C@@]1([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O

  • Target

    Autophagy; Reference Standards

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H315-H319

  • Precautions

    P264-P280-P302+P352-P305+P351+P338-P362+P364

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12-Ketochenodeoxycholic acid (Standard) [CAS 2458-08-4]

12-Ketochenodeoxycholic acid (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.