15-Keto latanoprost acid [CAS 369585-22-8]
15-Keto latanoprost acid [CAS 369585-22-8]
SKU:QM-0105610-01
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Product Details
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Description
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.1 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 μg/eye.
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CAS Number
[369585-22-8]
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Molecular Formula
C23H32O5
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Molecular Weight
388.5
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Smiles
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CCC(CCC2=CC=CC=C2)=O)C/C=C\CCCC(O)=O
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Target
Drug Metabolite
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Shipping Conditions
Room temperature
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Hazard Statement
H225-H302-H319-H336
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Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P330-P370+P378-P403+P233-P403+P235-P405-P501
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15-Keto latanoprost acid [CAS 369585-22-8]
15-Keto latanoprost acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.