17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid [CAS 1233715-33-7]
17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid [CAS 1233715-33-7]
SKU:QM-0124715-01
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Product Details
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Description
17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA). 17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy[1].
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CAS Number
[1233715-33-7]
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Molecular Formula
C22H32O3
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Molecular Weight
344.49
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Smiles
CC/C=C\CC(/C=C/C=C\C/C=C\C/C=C\CCCCCC(O)=O)=O
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Target
NF-κB; PPAR
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Isoform
PPARγ
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Shipping Conditions
Room temperature
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17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid [CAS 1233715-33-7]
17-Oxo-7 (Z),10 (Z),13 (Z),15 (E),19 (Z) -docosapentaenoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.