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(1R,3S) -Compound E [CAS 504428-17-5]

(1R,3S) -Compound E [CAS 504428-17-5]

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SKU:QM-0147616-01

£702.46 GBP
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  • Description

    (1R,3S) -Compound E is the isomer of Compound E , and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid (40), β-amyloid (42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.

  • CAS Number

    [504428-17-5]

  • Molecular Formula

    C27H24F2N4O3

  • Molecular Weight

    490.5

  • Smiles

    FC1=CC(F)=CC(CC(N[C@H](C)C(N[C@H]2N=C(C3=CC=CC=C3)C4=CC=CC=C4N(C2=O)C)=O)=O)=C1

  • Target

    γ-secretase

  • Purity

    99.82

  • Solubility

    DMSO : ≥ 50 mg/mL

  • Storage Conditions

    -20°C (Powder, protect from light)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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5 mgQM-0147616-01
5 mgQM-0147616-01
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10 mgQM-0147616-02
10 mgQM-0147616-02
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£855.00
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£855.00
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25 mgQM-0147616-03
25 mgQM-0147616-03
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£1,766.70
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£2,435.05/ea
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£1,766.70
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(1R,3S) -Compound E [CAS 504428-17-5]

(1R,3S) -Compound E is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.