β-Carboline-1-carboxylic acid [CAS 26052-96-0]
β-Carboline-1-carboxylic acid [CAS 26052-96-0]
SKU:QM-0016946-01
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Product Details
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Description
β-Carboline 1-carboxylic acid is a β-carboline alkaloid with anti-inflammatory, antifibrotic, antitumor and antibacterial activities. β-Carboline 1-carboxylic acid is the cAMP phosphodiesterase (IC50: 96 µM) and indoleamine 2, 3-dioxygenase (IDO) inhibitor. β-Carboline 1-carboxylic acid is cytotoxic to tumor cells. β-Carboline 1-carboxylic acid inhibits inflammation through the NF-κb/p65 pathway and can reverse epithelial-mesenchymal transition (EMT) . In addition, β-Carboline 1-carboxylic acid has strong inhibitory activity against S. aureus (IC50: 47.70 μg/mL) and E. coli (IC50: 19.17 μg/mL) [1][2][3][4].
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CAS Number
[26052-96-0]
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Molecular Formula
C12H8N2O2
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Molecular Weight
212.2
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Smiles
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)O
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Target
Bacterial; Indoleamine 2,3-Dioxygenase (IDO) ; NF-κB; Phosphodiesterase (PDE)
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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β-Carboline-1-carboxylic acid [CAS 26052-96-0]
β-Carboline-1-carboxylic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.