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(±) 2- (14,15-Epoxyeicosatrienoyl) glycerol [CAS 848667-56-1]
(±) 2- (14,15-Epoxyeicosatrienoyl) glycerol [CAS 848667-56-1]
SKU:QM-0080544
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Product Details
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Description
(±) 2- (14,15-Epoxyeicosatrienoyl) glycerol ((±) 2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. (±) 2- (14,15-Epoxyeicosatrienoyl) glycerol is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells. (±) 2- (14,15-Epoxyeicosatrienoyl) glycerol activates the metalloprotease ADAM17, which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway[1].
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CAS Number
[848667-56-1]
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Molecular Formula
C23H38O5
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Molecular Weight
394.54
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Smiles
OCC(CO)OC(CCC/C=C\C/C=C\C/C=C\CC1C(O1)CCCCC)=O
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Target
DNA/RNA Synthesis
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Shipping Conditions
Room temperature
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(±) 2- (14,15-Epoxyeicosatrienoyl) glycerol [CAS 848667-56-1]
(±) 2- (14,15-Epoxyeicosatrienoyl) glycerol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.