2,5-Di-tert-butylhydroquinone (Standard) [CAS 88-58-4]
2,5-Di-tert-butylhydroquinone (Standard) [CAS 88-58-4]
SKU:QM-0048226-01
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Product Details
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Description
2,5-Di-tert-butylhydroquinone (Standard) is the analytical standard of 2,5-Di-tert-butylhydroquinone. This product is intended for research and analytical applications. 2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor with an IC50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 (IC50: 1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1][2].
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CAS Number
[88-58-4]
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Molecular Formula
C14H22O2
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Molecular Weight
222.33
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Smiles
OC1=CC(C(C)(C)C)=C(O)C=C1C(C)(C)C
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Target
Calcium Channel; COX; Lipoxygenase; Reference Standards
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Shipping Conditions
Room temperature
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2,5-Di-tert-butylhydroquinone (Standard) [CAS 88-58-4]
2,5-Di-tert-butylhydroquinone (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.