2-Acetamidophenol (Standard) [CAS 614-80-2]
2-Acetamidophenol (Standard) [CAS 614-80-2]
SKU:QM-0110511-01
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Product Details
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Description
2-Acetamidophenol (Standard) is the analytical standard of 2-Acetamidophenol. This product is intended for research and analytical applications. 2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol. 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation[1][2].
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CAS Number
[614-80-2]
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Molecular Formula
C8H9NO2
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Molecular Weight
151.16
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Smiles
OC1=C(NC(C)=O)C=CC=C1
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Target
Ferroptosis; Glutathione Peroxidase; LDLR; Reactive Oxygen Species (ROS) ; Reference Standards
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Purity
99.45
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Storage Conditions
-20°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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2-Acetamidophenol (Standard) [CAS 614-80-2]
2-Acetamidophenol (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.