2-Ethylhexyl (E) -3- (4- (methoxy-d3) phenyl) acrylate [CAS 2734919-82-3]
2-Ethylhexyl (E) -3- (4- (methoxy-d3) phenyl) acrylate [CAS 2734919-82-3]
SKU:QM-0053177
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Product Details
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Description
2-Ethylhexyl (E) -3- (4- (methoxy-d3) phenyl) acrylate is the deuterium labeled Octinoxate. Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo[1][2][3][4][5].
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CAS Number
[2734919-82-3]
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Molecular Formula
C18H23D3O3
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Molecular Weight
293.42
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Smiles
CCCCC(COC(/C=C/C1=CC=C(C=C1)OC([2H])([2H])[2H])=O)CC
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Target
Androgen Receptor; Cytochrome P450; Estrogen Receptor/ERR; Isotope-Labeled Compounds; Thyroid Hormone Receptor
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Shipping Conditions
Room temperature
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2-Ethylhexyl (E) -3- (4- (methoxy-d3) phenyl) acrylate [CAS 2734919-82-3]
2-Ethylhexyl (E) -3- (4- (methoxy-d3) phenyl) acrylate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.