2-Methoxyestradiol-13C6
2-Methoxyestradiol-13C6
SKU:QM-0139883
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Product Details
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Description
2-Methoxyestradiol-13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
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Molecular Formula
C13 13C6H26O3
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Molecular Weight
308.36
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Smiles
[13CH3][13C@@]12[13C@]([13CH2][13CH2][13C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(OC)=C(O)C=C4CC3
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Target
Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Microtubule/Tubulin; Reactive Oxygen Species (ROS)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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2-Methoxyestradiol-13C6
2-Methoxyestradiol-13C6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.