3- (3-Hydroxyphenyl) propionic acid [CAS 621-54-5]
3- (3-Hydroxyphenyl) propionic acid [CAS 621-54-5]
SKU:QM-0199265-01
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Product Details
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Description
3- (3-Hydroxyphenyl) propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3- (3-Hydroxyphenyl) propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3- (3-Hydroxyphenyl) propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3- (3-Hydroxyphenyl) propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases[1].
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CAS Number
[621-54-5]
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Molecular Formula
C9H10O3
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Molecular Weight
166.18
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Smiles
O=C(O)CCC1=CC=CC(O)=C1
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Target
Endogenous Metabolite
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Isoform
Human Endogenous Metabolite; Microbial Metabolite
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Purity
99.89
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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3- (3-Hydroxyphenyl) propionic acid [CAS 621-54-5]
3- (3-Hydroxyphenyl) propionic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.