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3,5-Diiodothyropropionic acid (Standard) [CAS 1158-10-7]

3,5-Diiodothyropropionic acid (Standard) [CAS 1158-10-7]

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SKU:QM-0005284

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  • Description

    3,5-Diiodothyropropionic acid (Standard) is the analytical standard of 3,5-Diiodothyropropionic acid. This product is intended for research and analytical applications. 3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively. 3,5-Diiodothyropropionic acid promotes angiogenesis in 3-D human dermal microvascular endothelial cell sprouting assay. 3,5-Diiodothyropropionic acid prevents myocardial arteriolar loss in thyroidectomized rats and enhances cardiac energy-generating capacity in postinfarction heart failure rats. 3,5-Diiodothyropropionic can be used in studies related to angiogenesis and heart failure[1][2][3][4].

  • CAS Number

    [1158-10-7]

  • Molecular Formula

    C15H12I2O4

  • Molecular Weight

    510.06

  • Smiles

    O=C(O)CCC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1

  • Target

    Reference Standards; Thyroid Hormone Receptor

  • Shipping Conditions

    Room temperature

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3,5-Diiodothyropropionic acid (Standard) [CAS 1158-10-7]

3,5-Diiodothyropropionic acid (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.