3-Hydroxyphenylacetic acid [CAS 621-37-4]
3-Hydroxyphenylacetic acid [CAS 621-37-4]
SKU:QM-0195863-01
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Product Details
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Description
3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders[1][2][3][4].
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CAS Number
[621-37-4]
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Molecular Formula
C8H8O3
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Molecular Weight
152.15
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Smiles
OC1=CC=CC(CC(O)=O)=C1
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Target
Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Endogenous Metabolite; Ferroptosis; Glutathione Peroxidase; Keap1-Nrf2; Reactive Oxygen Species (ROS)
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Isoform
GPX4
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Purity
99.03
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Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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3-Hydroxyphenylacetic acid [CAS 621-37-4]
3-Hydroxyphenylacetic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.