3-Methylglutaric acid-d4 [CAS 1219798-68-1]
3-Methylglutaric acid-d4 [CAS 1219798-68-1]
SKU:QM-0058750
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Product Details
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Description
3-Methylglutaric acid-d4 is the deuterium labeled 3-Methylglutaric acid. 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration[1][2][3][4][5].
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CAS Number
[1219798-68-1]
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Molecular Formula
C6H6D4O4
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Molecular Weight
150.17
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Smiles
OC(C([2H])([2H])C(C)C([2H])([2H])C(O)=O)=O
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Target
Isotope-Labeled Compounds; Mitochondrial Metabolism; Na+/K+ ATPase; Reactive Oxygen Species (ROS)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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3-Methylglutaric acid-d4 [CAS 1219798-68-1]
3-Methylglutaric acid-d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.