(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside [CAS 408324-05-0]
(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside [CAS 408324-05-0]
SKU:QM-0024052
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Product Details
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Description
(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside is a diarylheptanol glycoside compound isolated from Tacca plantaginea. (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside significantly inhibit TNF-α-induced NF-κB transcriptional activity (IC50 = 9.4 μM) . (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside significantly activates PPAR transcriptional activity (EC50 = 9.9 μM) and has a specific activating effect on PPAR β (δ) (EC50 = 23.1 μM) . (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside is non-toxic to cells at the tested concentration. (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside can be used for research on inflammatory conditions[1].
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CAS Number
[408324-05-0]
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Molecular Formula
C25H34O11
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Molecular Weight
510.53
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Smiles
OC(C=C1CC[C@H](C[C@H](O)CCC2=CC(O)=C(C=C2)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C(C=C1)O
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Target
NF-κB; PPAR
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Shipping Conditions
Room temperature
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(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside [CAS 408324-05-0]
(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.