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(3R,5S) -Fluvastatin [CAS 155229-75-7]
(3R,5S) -Fluvastatin [CAS 155229-75-7]
SKU:QM-0066998
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Product Details
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Description
(3R,5S) -Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
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CAS Number
[155229-75-7]
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Molecular Formula
C24H26FNO4
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Molecular Weight
411.47
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Smiles
O=C(O)C[C@H](O)C[C@H](O)/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3
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Target
Autophagy; HMG-CoA Reductase (HMGCR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H312-H332
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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(3R,5S) -Fluvastatin [CAS 155229-75-7]
(3R,5S) -Fluvastatin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.