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4,4′-Secalonic acid D [CAS 2265910-52-7]
4,4′-Secalonic acid D [CAS 2265910-52-7]
SKU:QM-0023213
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Product Details
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Description
4,4′-Secalonic acid D (Compound 12) is a PARP1 inhibitor. 4,4′-Secalonic acid D induces the accumulation of ROS and DNA damage, activates the caspase-3/GSDME pathway, and triggers apoptosis and pyroptosis of tumor cells by inhibiting PARP1. 4,4′-Secalonic acid D has anti-tumor activity[1].
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CAS Number
[2265910-52-7]
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Molecular Formula
C32H30O14
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Molecular Weight
638.57
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Smiles
O[C@H]1[C@](C2=C(O)C[C@@H]1C)(C(OC)=O)OC3=C(C4=C(O[C@]5(C(OC)=O)C(C6=O)=C(O)C[C@H](C)[C@H]5O)C6=C(O)C=C4)C=CC(O)=C3C2=O
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Target
Apoptosis; Caspase; PARP; Pyroptosis; Reactive Oxygen Species (ROS)
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Shipping Conditions
Room temperature
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4,4′-Secalonic acid D [CAS 2265910-52-7]
4,4′-Secalonic acid D is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.