4-Methylhistamine (dihydrochloride) [CAS 36376-47-3]
4-Methylhistamine (dihydrochloride) [CAS 36376-47-3]
SKU:QM-0112591-01
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Product Details
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Description
4-Methylhistamine hydrochloride is the dihydrochloride salt of 4-Methylhistamine. 4-Methylhistamine is a potent and selective agonist of histamine 4 receptor (H4R) with a Ki of 50 nM. 4-Methylhistamine has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine can potently activate the hH4R (pEC50 = 7.4). 4-Methylhistamine can be used for the researches of cancer, inflammation and immunology, such as lung cancer and skin inflammation[1][2][3][4].
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CAS Number
[36376-47-3]
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Molecular Formula
C6H13Cl2N3
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Molecular Weight
198.1
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Smiles
[H]Cl.CC1=C(CCN)NC=N1.[H]Cl
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Target
Histamine Receptor
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Isoform
H4 Receptor
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Purity
99.35
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Solubility
DMSO : 20 mg/mL (ultrasonic; warming) |H2O : 125 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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4-Methylhistamine (dihydrochloride) [CAS 36376-47-3]
4-Methylhistamine (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.