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(4R,5S) -Monomethyl auristatin E intermediate-6
(4R,5S) -Monomethyl auristatin E intermediate-6
SKU:QM-0074492
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Product Details
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Description
(4R,5S) -Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E. Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs).
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Molecular Formula
C20H29NO5
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Molecular Weight
363.45
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Smiles
CC[C@H](C)[C@@H](NC(OCC1=CC=CC=C1)=O)C(CC(OC(C)(C)C)=O)=O
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Target
Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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(4R,5S) -Monomethyl auristatin E intermediate-6
(4R,5S) -Monomethyl auristatin E intermediate-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.