5- (N, N-Hexamethylene) -amiloride (Standard) [CAS 1428-95-1]
5- (N, N-Hexamethylene) -amiloride (Standard) [CAS 1428-95-1]
SKU:QM-0005396-01
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Product Details
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Description
5- (N, N-Hexamethylene) -amiloride (Standard) is the analytical standard of 5- (N, N-Hexamethylene) -amiloride. This product is intended for research and analytical applications. 5- (N, N-Hexamethylene) -amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5- (N, N-Hexamethylene) -amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively[1][2].
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CAS Number
[1428-95-1]
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Molecular Formula
C12H18ClN7O
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Molecular Weight
311.77
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Smiles
O=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N
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Target
Apoptosis; HIV; Reference Standards; Sodium Channel
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Shipping Conditions
Room temperature
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5- (N, N-Hexamethylene) -amiloride (Standard) [CAS 1428-95-1]
5- (N, N-Hexamethylene) -amiloride (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.