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A2764 (dihydrochloride) [CAS 861038-72-4]

A2764 (dihydrochloride) [CAS 861038-72-4]

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QM-0145219-01

£111.63 GBP
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Product Details

  • Description

    A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1), which has moderate inhibitory effects on TREK-1 and TALK-1. A2764 dihydrochloride is more sensitive to the activated mTRESK channels (IC50=6.8 μM) than the basal current. A2764 dihydrochloride can lead to cell depolarization and increased excitability in native cells, it has the potential for probing the role of TRESK channel in migraine and nociception[1].

  • CAS Number

    [861038-72-4]

  • Molecular Formula

    C15H21Cl3N2O

  • Molecular Weight

    351.7

  • Smiles

    ClC1=C2C=CC=NC2=C(OCCN(CC)CC)C=C1.[H]Cl.[H]Cl

  • Target

    Potassium Channel

  • Concentration

    10mM

  • Purity

    99.05

  • Solubility

    DMSO : 41.67 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0145219-01
5 mgQM-0145219-01
£111.63/ea		 £0.00
£111.63/ea £0.00
10 mM - 1 mLQM-0145219-02
10 mM - 1 mLQM-0145219-02
£120.63/ea		 £0.00
£120.63/ea £0.00
10 mgQM-0145219-03
10 mgQM-0145219-03
£200.66/ea		 £0.00
£200.66/ea £0.00
25 mgQM-0145219-04
25 mgQM-0145219-04
£331.88/ea		 £0.00
£331.88/ea £0.00
50 mgQM-0145219-05
50 mgQM-0145219-05
£489.83/ea		 £0.00
£489.83/ea £0.00
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A2764 (dihydrochloride) [CAS 861038-72-4]

A2764 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.