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Abexinostat [CAS 783355-60-2]
Abexinostat [CAS 783355-60-2]
SKU:QM-0136608-01
£70.54 GBP
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Product Details
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Description
Abexinostat (CRA 024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM. Abexinostat also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC50 below 10 nM[1][4].
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CAS Number
[783355-60-2]
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Molecular Formula
C21H23N3O5
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Molecular Weight
397.42
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Smiles
O=C(NCCOC1=CC=C(C=C1)C(NO)=O)C2=C(C3=CC=CC=C3O2)CN(C)C
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Target
HDAC
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Isoform
HDAC1; HDAC10; HDAC2; HDAC3; HDAC6; HDAC8
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Purity
99
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Solubility
DMSO : 3.33 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H312, H332
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Precautions
H302, H312, H332
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Abexinostat [CAS 783355-60-2]
Abexinostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.