Acetohexamide [CAS 968-81-0]
Acetohexamide [CAS 968-81-0]
SKU:QM-0159058-01
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Product Details
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Description
Acetohexamide is an orally active first-generation sulfonylurea agent used in research related to type 2 diabetes and cancer. Acetohexamide exerts reductase activity in human erythrocytes. Acetohexamide stimulates the pancreas to secrete insulin. Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas. Acetohexamide can inhibit the formation of circular chemorepellent induced defects (CCIDs) in lymphendothelial cell (LEC) monolayers. Acetohexamide inhibits markers of epithelial-to-mesenchymal-transition and migration. Acetohexamide suppresses the synthesis of 12 (S) -HETE. Acetohexamide can potentiate hypoglycaemic action[1][2][3][4].
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CAS Number
[968-81-0]
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Molecular Formula
C15H20N2O4S
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Molecular Weight
324.4
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Smiles
O=S(C1=CC=C(C(C)=O)C=C1)(NC(NC2CCCCC2)=O)=O
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Target
Potassium Channel
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Purity
99.67
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H312, H332
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Precautions
H302, H312, H332
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Acetohexamide [CAS 968-81-0]
Acetohexamide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.