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Aclacinomycin A (hydrochloride) [CAS 75443-99-1]

Aclacinomycin A (hydrochloride) [CAS 75443-99-1]

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SKU:QM-0001003

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  • Description

    Aclacinomycin A (Aclarubicin) hydrochloride is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A hydrochloride is an inhibitor of topoisomerase I and II. Aclacinomycin A hydrochloride inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A hydrochloride might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis[1][2][3].

  • CAS Number

    [75443-99-1]

  • Molecular Formula

    C42H54ClNO15

  • Molecular Weight

    848.33

  • Smiles

    O=C([C@@H]1C2=CC(C(C3=CC=CC(O)=C43)=O)=C(C4=O)C(O)=C2[C@@H](O[C@@](O[C@@H](C)[C@H]5O[C@@](O[C@@H](C)[C@H]6O[C@](CCC7=O)([H])O[C@H]7C)([H])C[C@@H]6O)([H])C[C@@H]5N(C)C)C[C@]1(O)CC)OC.Cl

  • Target

    Antibiotic; DNA/RNA Synthesis; Proteasome; Topoisomerase

  • Isoform

    Topo I; Topo II

  • Purity

    95.16

  • Solubility

    10 mM in H2O|DMSO : ≥ 125 mg/mL

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture and light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H301-H311-H331

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

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Aclacinomycin A (hydrochloride) [CAS 75443-99-1]

Aclacinomycin A (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.