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Afegostat (hydrochloride) [CAS 161302-93-8]
Afegostat (hydrochloride) [CAS 161302-93-8]
SKU:QM-0109146
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Product Details
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Description
Afegostat hydrochloride (D-Isofagomine hydrochloride) is a potent β-galactosidase inhibitor with activity ameliorating GM1-gangliosidosis and Morquio B disease-associated mutations. Afegostat hydrochloride is able to induce the maturation of mutant β-galactosidase in fibroblasts from patients with GM1-gangliosidosis. Afegostat hydrochloride also promotes the reduction of keratin sulfate and oligosaccharide load in patient cells[1].
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CAS Number
[161302-93-8]
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Molecular Formula
C6H14ClNO3
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Molecular Weight
183.63
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Smiles
OC[C@@H]1[C@H]([C@@H](CNC1)O)O.Cl
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Target
Glycosidase
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Shipping Conditions
Room temperature
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Afegostat (hydrochloride) [CAS 161302-93-8]
Afegostat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.