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Agerafenib hydrochloride [CAS 1227678-26-3]
Agerafenib hydrochloride [CAS 1227678-26-3]
SKU:QM-0000539
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Product Details
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Description
Agerafenib hydrochloride is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.
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CAS Number
[1227678-26-3]
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Molecular Formula
C24H23ClF3N5O5
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Molecular Weight
553.92
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Smiles
O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2.[H]Cl
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Target
Raf
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Isoform
B-Raf; C-Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Agerafenib hydrochloride [CAS 1227678-26-3]
Agerafenib hydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.