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AKT-IN-12 [CAS 2396718-52-6]
AKT-IN-12 [CAS 2396718-52-6]
SKU:QM-0067346
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Product Details
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Description
AKT-IN-12 (compound 3e) is a potent Akt kinase inhibitor with an IC50 value of 0.55 μM. AKT-IN-12 induces G0/G1 cell cycle arrest and apoptosis. AKT-IN-12 also inhibits p-AKT, p-ERK, and activates p-JNK, JNK. AKT-IN-12 can be used for researching leukemia[1].
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CAS Number
[2396718-52-6]
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Molecular Formula
C42H46N2O7S
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Molecular Weight
722.89
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Smiles
[H][C@@]12CC3=CC=C(OC4=CC(C[C@]5(C6=C(C(OC(C7CCCS7)=O)=C(C=C6CCN5C)OC)OC8=C(C=C(C2=C8)CCN1C)OC)[H])=CC=C4OC)C=C3
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Target
Akt; Apoptosis
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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AKT-IN-12 [CAS 2396718-52-6]
AKT-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.