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Akt/mTOR-IN-1
Akt/mTOR-IN-1
SKU:QM-0117169
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Product Details
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Description
Akt/mTOR-IN-1 (Compound 8r) is an AKT/mTOR signaling pathway inhibitor exhibiting an IC50 value of 0.8 µM with anticancer activity. Akt/mTOR-IN-1 can decrease the expression of Caspase 3 and increase the expression of the autophagic protein Cyclin B1, thereby inducing cell autophagy and apoptosis. Akt/mTOR-IN-1 can be used in research related to non-small cell lung cancer (NSCLC) [1].
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Molecular Formula
C31H21F3N2O3
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Molecular Weight
526.51
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Smiles
O=C1NC(C2(O)C=CC(C=C2)=O)=C(C3=CC=C(C(F)(F)F)C=C3)C4=C1N(CC5=CC=CC=C5)C6=C4C=CC=C6
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Target
Akt; Caspase; CDK; mTOR
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Isoform
Caspase 3
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Shipping Conditions
Room temperature
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Akt/mTOR-IN-1
Akt/mTOR-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.